10Panx (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-L-tyrosine, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C58H79N15O16 • XCF3COOH

Formula Weight: 1242,3

Shelf life (days): 1460

Notes: 10Panx is a peptide mimetic of the pannexin 1 (PANX1) ectodomain and inhibitor of PANX1, an innexin family gap domain protein and component of membrane channels.{65334} It inhibits purinergic P2X7 receptor activation-induced dye uptake, constitutive dye uptake, and hemichannel currents, as well as ATP-induced caspase activation and IL-1β release in HEK293 cells when used at a concentration of 200 µM. 10Panx inhibits pannexin channel currents and connexin 46 channel currents in Xenopus oocytes expressing the human channels.{65335}

• SKU: CAY36867-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36867-25
• Package Unit: 25 mg
• Quantity Unit: STK
• Application: Reinstoffe