Formulation: An oil
Formal Name: (2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
Purity: ≥65%
Formula Markup: C20H28O
Formula Weight: 284,4
Shelf life (days): 730
CAS Number: 564-87-4
Notes: 11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin.{29223} When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal (Item No. 18449) beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light.{38067} In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.{38066}
English
Deutsch
