Formulation: A solution in ethanol
Formal Name: rel-12-[(2R,3S)-3-(2Z)-2-octen-1-yl-2-oxiranyl]-7Z,10Z-dodecadienoic acid
Purity: ≥98%
Formula Markup: C22H36O3
Formula Weight: 348,5
Shelf life (days): 365
CAS Number: 355016-19-2
Notes: (±)13,14-EDT is an oxylipin and a metabolite of adrenic acid (Item No. 90300) formed via the cytochrome P450 (CYP) pathway.{72007,72008} It activates large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells when used at a concentration of 50 nM and induces dilation of isolated porcine arterioles (EC50 = 12 pM).{52399} (±)13,14-EDT also induces relaxation of isolated bovine coronary arteries precontracted with the TP receptor agonist U-46619 (Item No. 16450).{72008}