Formulation: A solution in ethanol
Formal Name: 7Z,10Z,13Z,15E,19Z-17-oxo-docosapentaenoic acid
Purity: ≥95%
Formula Markup: C22H32O3
Formula Weight: 344,5
Shelf life (days): 365
CAS Number: 1233715-33-7
Notes: Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity.{16993,18161} It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).{18161}