17α-Hydroxyprogesterone, CAS 68-96-2

Formulation: A crystalline solid

Formal Name: 17-hydroxy-pregn-4-ene-3,20-dione

Purity: ≥98%

Formula Markup: C21H30O3

Formula Weight: 330,5

Shelf life (days): 1460

CAS Number: 68-96-2

Notes: 17α-Hydroxyprogesterone (17-OHP) is a steroid and precursor in the synthesis of adrenal androgens.{54784,54785} It binds to the glucocorticoid receptor in a cell-free assay (IC50 = 82 nM for the human receptor) and induces glucocorticoid receptor transactivation in HEK293 cells (EC50 = 1.2 µM).{54785} 17-OHP (0.005-1 µM) inhibits aldosterone-induced transactivation of the mineralocorticoid receptor in cell-based assays.{54784} Serum levels of 17-OHP are increased in patients with congenital adrenal hyperplasia.{54784,54785}

• SKU: CAY33154-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33154-5
• Green Labware: No
• Package Unit: 5 g
• Quantity Unit: STK