2-Methylthioadenosine triphosphate (sodium salt), CAS 100020-57-3

Formulation: A solution in water

Formal Name: 2-(methylthio)-adenosine 5'-(tetrahydrogen triphosphate), tetrasodium salt

Purity: ≥95%

Formula Markup: C11H14N5O13P3S • 4Na

Formula Weight: 641,2

Shelf life (days): 730

CAS Number: 100020-57-3

Notes: 2-Methylthioadenosine triphosphate is an agonist of the purinergic P2X2 and P2Y1 receptors.{33411,33412} It is also an inhibitor of guanylate cyclase C (GC-C) in rat intestinal mucosal membranes (Ki = 360 µM in the presence of E. coli heat-stable enterotoxin).{66334} 2-Methylthioadenosine triphosphate (1 µM) induces calcium influx in primary rat arcuate nucleus neurons in a fluorescence-based reporter assay.{33411} It increases inositol phosphate accumulation in 1321N1 astrocytoma cells expressing human P2Y1 receptors (EC50 = 51 nM).{33412} 2-Methylthioadenosine triphosphate inhibits uroguanylin-induced increases in urine flow and sodium excretion in rats.{66333}

• SKU: CAY21418
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21418-2.8
• Package Unit: 2.8 mg
• Quantity Unit: STK
• Application: GC-MS