2-Phenylaminoadenosine, CAS 53296-10-9

2-Phenylaminoadenosine, CAS 53296-10-9
SKU
CAY28734-5
Packaging Unit
5 mg
Manufacturer
Cayman Chemical

Availability: loading...
Price is loading...
Formulation: A solid

Purity: ≥98%

Formula Markup: C16H18N6O4

Formula Weight: 358,4

Shelf life (days): 1460

CAS Number: 53296-10-9

Notes: 2-Phenylaminoadenosine is an adenosine receptor agonist.{48560} It binds to adenosine A1 receptors in rat cortical membranes (IC50 = 910 nM) and A2 receptors in rat striatal membranes (IC50 = 115 nM). 2-Phenylaminoadenosine increases coronary flow in a perfused working rat heart model ex vivo (EC25 = 110 nM). It decreases blood pressure in normotensive (ED25 = 28 μg/kg) and spontaneously hypertensive rats (SHR; ED30 = 5.32 μg/kg).{48560,48561} 2-Phenylaminoadenosine (500 nmol/kg) increases L-dihydroxyphenylalanine (L-DOPA; Item No. 13248) accumulation in rat striatum.{48562} It also inhibits conditioned avoidance responding (CAR) to electric shock in rats (ED50 = 1.3 mg/kg).{48563}
More Information
SKU CAY28734-5
Manufacturer Cayman Chemical
Manufacturer SKU 28734-5
Green Labware No
Package Unit 5 mg
Quantity Unit STK
Product information (PDF) Download
MSDS (PDF) Download