3,5-Diiodo-L-thyronine, CAS 1041-01-6

Formulation: A solid

Formal Name: O-(4-hydroxyphenyl)-3,5-diiodo-L-tyrosine

Purity: ≥98%

Formula Markup: C15H13I2NO4

Formula Weight: 525,1

Shelf life (days): 1460

CAS Number: 1041-01-6

Notes: 3,5-Diiodo-L-thyronine (3,5-T2) is a thyroid hormone metabolite.{64130} It binds to thyroid hormone receptor α1 (TRα1), TRβ1, and TRβ2 (EC50s = 0.8, 0.79, and 0.1 µM, respectively, in cell-free assays).{64131} 3,5-T2 (1 pM) stimulates oxygen consumption in perfused livers isolated from rats with hypothyroidism induced by sodium iodide.{64132} It reduces subcutaneous and epididymal fat mass, as well as decreases serum leptin and cholesterol levels, without affecting body weight in high-fat diet-induced obese mice when administered at a dose of 2.5 µg/g per day.{64130}

• SKU: CAY35212-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35212-10
• Green Labware: No
• Package Unit: 10 g
• Quantity Unit: STK