Formulation: A crystalline solid
Formal Name: 3-hydroxy-octanoic acid
Purity: ≥98%
Formula Markup: C8H16O3
Formula Weight: 160,2
Shelf life (days): 1460
CAS Number: 14292-27-4
Notes: 3-hydroxy Octanoic acid is a hydroxylated fatty acid that has been found in LPS from P. aeruginosa and the methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by P. oleovorans.{31684,40824} It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils which endogenously express GPR109B.{41639} 3-hydroxy Octanoic acid prevents lipolysis of human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxy Octanoic acid also increase 3.41-fold in human male runners following a treadmill run to exhaustion as well as in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.{41640,41641} [Matreya, LLC. Catalog No. 1745]
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