(3S)-hydroxy Quinidine, CAS 53467-23-5

Formulation: A solid

Formal Name: 6'-methoxy-cinchonan-3,9S-diol

Purity: ≥98%

Formula Markup: C20H24N2O3

Formula Weight: 340,4

Shelf life (days): 1460

CAS Number: 53467-23-5

Notes: (3S)-hydroxy Quinidine is an active quinidine metabolite.{38062} Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.{36200,36201}

• SKU: CAY23411-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 23411-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK