Formulation: A solid
Formal Name: N-[3-[2-(acetylamino)ethyl]-1H-indol-5-yl]-carbamic acid, methyl ester
Purity: ≥95%
Formula Markup: C14H17N3O3
Formula Weight: 275,3
Shelf life (days): 1460
CAS Number: 190277-13-5
Notes: 5-Methoxycarbonylamino-N-acetyltryptamine (5-MCA-NAT) is a melatonin (Item No. 14427) derivative and a partial agonist of melatonin receptor 1 (MT1) and MT2.{72088} It inhibits forskolin-induced production of cAMP in CHO cells expressing human MT1 or MT2 (EC50s = 440 and 98 nM, respectively). In vivo, ocular administration of 5-MCA-NAT reduces intraocular pressure in control and DBA/2J glaucomatous mice.{72089}