Formulation: A solution in ethanol
Formal Name: 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid
Purity: ≥95%
Formula Markup: C20H30O3
Formula Weight: 318,5
Shelf life (days): 365
CAS Number: 106154-18-1
Notes: 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.{2090} It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM.{1434} 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils via a specific G protein-coupled receptor.{2793,3036,10476,11003}