Formulation: A crystalline solid
Formal Name: 2-(2,4-dimethoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
Purity: ≥95%
Formula Markup: C18H16O5
Formula Weight: 312,3
Shelf life (days): 1460
CAS Number: 720675-74-1
Notes: 6,2',4'-Trimethoxyflavone is a flavonoid that has been found in T. acutifolius and has diverse biological activities.{58257,58258,58259} It acts as an antagonist of the aryl hydrocarbon receptor (AhR), inhibiting benzo[a]pyrene-induced AhR-dependent transcription in a reporter assay when used at concentrations of 2 and 10 µM.{58257} 6,2',4'-Trimethoxyflavone decreases LPS-induced production of TNF-α in THP-1 cells (IC50 = 47.7 µg/ml).{58258} It inhibits cell migration and invasion, but not proliferation, of HN-30 head and neck squamous cell carcinoma (HNSCC) cells in vitro when used at a concentration of 10 µM.{58259}
English
Deutsch
