6-O-desmethyl Donepezil, CAS 120013-56-1

Formulation: A solid

Formal Name: 2,3-dihydro-6-hydroxy-5-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one

Purity: ≥95%

Formula Markup: C23H27NO3

Formula Weight: 365,5

Shelf life (days): 1460

CAS Number: 120013-56-1

Notes: 6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil (Item No. 13245).{42676} It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6.{42677} It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 µM in HEK293 cells expressing hERG).{42676}

• SKU: CAY27175-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27175-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK