8-M-PDOT, CAS 134865-70-6

Formulation: A crystalline solid

Formal Name: N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-propanamide

Purity: ≥98%

Formula Markup: C14H19NO2

Formula Weight: 233,3

Shelf life (days): 1460

CAS Number: 134865-70-6

Notes: 8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM).{26021} It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson's disease.{47781}

• SKU: CAY29521-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29521-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK