Formulation: A crystalline solid
Formal Name: N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-propanamide
Purity: ≥98%
Formula Markup: C14H19NO2
Formula Weight: 233,3
Shelf life (days): 1460
CAS Number: 134865-70-6
Notes: 8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM).{26021} It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson's disease.{47781}