Formulation: A solid
Formal Name: (9Z,11E)-9,11-octadecadienoic acid, monosodium salt
Purity: ≥98%
Formula Markup: C18H31O2 • Na
Formula Weight: 302,4
Shelf life (days): 1460
CAS Number: 756499-04-4
Notes: 9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid (Item Nos. 90150 / 90150.1 / 21909) that has been found in beef and milk fat.{6849} It binds to peroxisome proliferator-activated receptor α (PPARα; IC50 = 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 µM.{15462} 9(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-induced GLUT4 expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.{59110} Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration in ob/ob mice. It also increases body weight gain and body fat in weanling mice.{10568} [Matreya, LLC. Catalog No. 1278]
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