A-1596586, CAS 1918142-34-3

Formulation: A solid

Formal Name: 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[(2R,4R)-2-(3,4-dimethoxyphenyl)-3,4-dihydro-7-methoxy-2H-1-benzopyran-4-yl]-cyclopropanecarboxamide

Purity: ≥98%

Formula Markup: C29H27F2NO7

Formula Weight: 539,5

Shelf life (days): 1460

CAS Number: 1918142-34-3

Notes: A-1596586 is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) bearing the F508 deletion (F508del) mutation.{68883} It increases CFTR levels in CFBE41o- bronchial epithelial cells expressing F508del-CFTR fused to HRP (EC50 = 0.13 µM) and the transepithelial current in primary human bronchial epithelial cells isolated from a patient with cystic fibrosis with the F508del-CFTR mutation (EC50 = 0.028 µM).

• SKU: CAY41316-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41316-5
• Package Unit: 5 mg
• Quantity Unit: STK