α-CGRP (8-37) (human) (trifluoroacetate salt)

Formulation: A lyophilized powder

Purity: ≥95%

Formula Markup: C139H230N44O38 • XCF3COOH

Formula Weight: 3125,6

Shelf life (days): 1460

Notes: Calcitonin gene-related protein (CGRP) is a neuropeptide and a product of alternative splicing of the calcitonin gene.{41392,41390} It induces vasodilation of both arteries and veins in addition to various non-vascular biological activities. α-CGRP (8-37) is an antagonist of CGRP receptors (IC50 = 4.9 nM in SK-N-MC cells expressing the human receptor) that inhibits CGRP-induced vasodilation.{41390,41393} In a mouse model of headache, α-CGRP (8-37) application to the dura mater reduces behavior induced by application of capsaicin and inflammatory mediators.{41391} α-CGRP (8-37) (human) is a peptide fragment derived from the human CGRP protein sequence.

• SKU: CAY24406-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24406-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK