A2764 (hydrochloride), CAS 861038-72-4

Formulation: A solid

Formal Name: 2-[(5-chloro-8-quinolinyl)oxy]-N,N-diethyl-ethanamine, dihydrochloride

Purity: ≥98%

Formula Markup: C15H19ClN2O • 2HCl

Formula Weight: 351,7

Shelf life (days): 1460

CAS Number: 861038-72-4

Notes: A2764 is an inhibitor of the two-pore domain potassium channel K2P18.1/TRESK (IC50 = 11.8 µM in ionomycin-stimulated Xenopus oocytes expressing the mouse receptor).{65336} It is selective for K2P18.1/TRESK over K2P2.1/TREK1, K2P10.1/TREK2, K2P4.1/TRAAK, K2P3.1/TASK1, K2P3.2/TASK2, K2P3.3/TASK3, K2P16.1/TALK1, and K2P13.1/THIK1 at 100 µM. A2764 (100 µM) inhibits basal potassium currents in isolated mouse dorsal root ganglion neurons.

• SKU: CAY36943-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36943-100
• Package Unit: 100 mg
• Quantity Unit: STK
• Application: Reinstoffe