A2AR Agonist-1, CAS 41552-95-8

Formulation: A solid

Formal Name: N-[2-(1H-indol-3-yl)ethyl]-adenosine

Purity: ≥98%

Formula Markup: C20H22N6O4

Formula Weight: 410,4

Shelf life (days): 1460

CAS Number: 41552-95-8

Notes: A2AR agonist-1 is an agonist of the adenosine A2A receptor and an inhibitor of equilibrative nucleoside transporter 1 (ENT1; Kis = 4.39 and 3.47 µM for the human receptor and guinea pig transporter, respectively).{50081} It decreases adenosine uptake by 80% in PC12 cells when used at a concentration of 61 µM and increases brain levels of adenosine in a transgenic mouse model of Huntington’s disease when administered at a dose of 20 mg/kg.{47653} A2AR agonist-1 (0.11 mg/kg) also rescues motor performance and increases survival in a transgenic mouse model of Huntington’s disease.

• SKU: CAY28414-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28414-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK