AA92593, CAS 457961-34-1

Formulation: A solid

Formal Name: 1-[(4-methoxy-3-methylphenyl)sulfonyl]-piperidine

Purity: ≥98%

Formula Markup: C13H19NO3S

Formula Weight: 269,4

Shelf life (days): 1460

CAS Number: 457961-34-1

Notes: AA92593 is an opsin 4 (OPN4) receptor antagonist (Ki = 16 nM).{65240} It inhibits light-induced calcium transients in CHO cells expressing human OPN4 (IC50 = 665 nM). AA92593 (10 µM) reverses light-induced calcium influx in rat intrinsically photosensitive retinal ganglion cells (ipRGCs). In vivo, AA92593 (30 mg/kg) reduces light-induced pupil constriction in mice.

• SKU: CAY35836-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35836-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe