Acebutolol, CAS 37517-30-9

Formulation: A solid

Formal Name: N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-butanamide

Purity: ≥95%

Formula Markup: C18H28N2O4

Formula Weight: 336,4

Shelf life (days): 1460

CAS Number: 37517-30-9

Notes: Acebutolol is an antagonist of β1-adrenergic receptors (β1-ARs; Ki = 125 nM).{26306} It is selective for β1- over β2-ARs (Ki = 7,070 nM). In vivo, acebutolol decreases isoprenaline-induced tachycardia and diastolic hypotension in cats (ED50 = 0.09 mg/kg for both).{39375} Acebutolol (12.5, 25, and 50 mg/kg) inhibits ouabain-induced arrhythmias in rabbits, as well as protects against chloroform-induced ventricular fibrillation in mice (ED50 = 0.067 mg/kg).{39376} Formulations containing acebutolol have been used in the treatment of angina and irregular heartbeat.

• SKU: CAY36534-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36534-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK
• Application: Reinstoffe