ACTH (1-16) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Formulation: A solid

Formal Name: α1-16-corticotropin, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C89H133N25O22S • XCF3COOH

Formula Weight: 1937,2

Shelf life (days): 1460

Notes: ACTH (1-16) is a peptide fragment of adrenocorticotropic hormone (ACTH; Item No. 24257), a peptide hormone found in the brain that is involved in the biological stress response.{45140} It binds to melanocortin receptors (MCRs; Kis = 0.267, 19, 698, and 2,600 nM for MC1R, MC3R, MC4R, and MC5R, respectively).{48427} ACTH (1-16) (160 µg/kg, i.v.) increases mean arterial blood pressure (MAP) following bleeding-induced hypotension in a rat model of hemorrhagic shock 15-30 minutes after administration.{48428} It increases grooming behavior and the incidence of stretching and yawning syndrome (SYS) in rats when administered intraventricularly at 0.05 or 2 μg.{47599}

• SKU: CAY27273-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27273-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK