ACTH (1-39) (trifluoroacetate salt)

Formulation: A lyophilized powder

Purity: ≥95%

Formula Markup: C207H308N56O58S • XCF3COOH

Formula Weight: 4541,1

Shelf life (days): 1460

Notes: ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor.{38619} It induces accumulation of cAMP and release of corticosterone from rat adrenal cells in a concentration-dependent manner.{38620} ACTH (1-39) also protects neurons from death induced by staurosporine (Item No. 81590), glutamate, NMDA (Item No. 14581), AMPA (Item No. 14571), kainate, quinolinic acid (Item No. 14941), and reactive oxygen species when used at a concentration of 400 nM.{38621} Formulations containing ACTH (1-39) have been used in the treatment of systemic lupus erythematosus.

• SKU: CAY24257
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24257-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK