Formulation: A crystalline solid
Formal Name: 3'-adenylic acid, sodium salt, hydrate
Purity: ≥98%
Formula Markup: C10H14N5O7P • XNa [XH2O]
Formula Weight: 347,2
Shelf life (days): 1460
Notes: Adenosine 3'-monophosphate is a nucleotide and metabolite formed via hydrolysis of 2',3'-cAMP by metal-dependent phosphodiesterases.{49038} It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2B receptor antagonist MRS1754.{49039} Adenosine 3'-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine (Item No. 21232).