Formulation: A solid
Formal Name: N-[4-[2-[[4-[2-[(2-aminoethyl)amino]-2-oxoethyl]phenyl]amino]-2-oxoethyl]phenyl]-adenosine
Purity: ≥98%
Formula Markup: C28H32N8O6
Formula Weight: 576,6
Shelf life (days): 1460
CAS Number: 96760-69-9
Notes: Adenosine amine congener (ADAC) is an adenosine A1 receptor agonist.{62321,62322} It selectively binds adenosine A1 over A2A and A3 receptors (Kis = 0.85, 210, and 281 nM, respectively, for the rat receptors).{62323} ADAC (75 µg/kg) increases survival and prevents neuronal damage in the hippocampal CA1 region in a gerbil model of cerebral ischemia induced by bilateral carotid artery occlusion.{62321} It protects against auditory threshold shifts and inner and outer hair cell loss in rats following noise exposure at 110 dB when administered at a dose of 100 µg/kg.{62322}