ADL5859 (hydrochloride), CAS 850173-95-4

Formulation: A solid

Formal Name: N,N-diethyl-4-(5-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-4-yl)-benzamide, monohydrochloride

Purity: ≥98%

Formula Markup: C24H28N2O3 • HCl

Formula Weight: 429

Shelf life (days): 1460

CAS Number: 850173-95-4

Notes: ADL5859 is a δ-opioid receptor agonist (Ki = 0.84 nM).{45386} It is selective for δ-opioid receptors over μ-opioid and κ-opioid receptors exhibiting 32 and 37% inhibition, respectively, in radioligand binding assays when used at a concentration of 10 μM. ADL5859 (3 mg/kg) completely reverses mechanical hyperalgesia induced by complete Freund’s adjuvant (CFA) in rats. It also decreases immobility time in the forced swim test in rats, indicating antidepressant-like activity.

• SKU: CAY27796-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27796-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK