Formulation: A solid
Formal Name: 3-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2-hydroxy-4-methoxy-6-(2-phenylethyl)-benzoic acid
Purity: ≥97%
Formula Markup: C26H32O4
Formula Weight: 408,5
Shelf life (days): 1460
CAS Number: 78916-42-4
Notes: Amorfrutin B is a partial agonist of the peroxisome proliferator-activated receptor γ (PPARγ; Ki = 19 nM and EC50 = 73 nM) that was first isolated from A. fruticosa.{31276} It binds to PPARα and PPARβ/δ with Ki values of 2.6 and 1.7 µM, respectively.{31276} In insulin-resistant mice, 100 mg/kg/day amorfrutin B is reported to improve insulin sensitivity, glucose tolerance, and plasma lipid concentrations after two weeks of treatment.{31276}