Formulation: A solid
Formal Name: (7R,14R,14aR)-1,3,4,6,7,13,14,14a-octahydro-7,14-methano-2H,11H-dipyrido[1,2-a:1′,2′-e][1,5]diazocin-11-one
Purity: ≥95%
Formula Markup: C15H20N2O
Formula Weight: 244,3
Shelf life (days): 1460
CAS Number: 486-89-5
Notes: Anagyrine is an alkaloid that has been found in L. albus and has diverse biological activities.{53991,53992,53415} It binds to muscarinic and nicotinic acetylcholine receptors (AChRs) with IC50 values of 132 and 2,096 µM, respectively, in radioligand binding assays using pig brain membranes, which endogenously express high levels of the receptors.{53991} It inhibits proliferation of TE 671 and SH-SY5Y cancer cells (EC50s = 18.1 and 19.1 µM, respectively).{53415} Maternal ingestion of anagyrine during gestation is associated with the teratogenic condition crooked calf disease in cattle.{53993}
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