Formulation: A lyophilized powder
Formal Name: 5-L-isoleucine-angiotensin I, trifluroracetate salt
Purity: ≥95%
Formula Markup: C62H89N17O14 • XCF3COOH
Formula Weight: 1296,5
Shelf life (days): 1460
Notes: Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II (Item No. 17150) by angiotensin-converting enzyme (ACE).{40801} It binds to angiotensin receptors in human myometrium membrane preparations (Kd = 11.2 nM) and increases renal vascular resistance in isolated rat kidney (EC50 = 10.5 nM).{40802,40803} In vivo, angiotensin I (5 μg/kg, i.c.v.) increases mean arterial pressure (MAP) and plasma arginine vasopressin (AVP) level in fetal ewes.{40804}