Anle138b, CAS 882697-00-9

Synuclein aggregation inhibitor

Product Type: Inhibitor

CAS No.: 882697-00-9

MolecularFormula: C16H11BrN2O2

Molecular Weight: 343,2

Source: Synthetic

Purity: >98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (15 mg/ml, warm)

Appearance: White powder

PubChem CID: 44608289

Scientific Background: Anle138b is an oligomeric aggregation inhibitor that inhibits the formation of pathological prion protein (PrPSc) and α-synuclein aggregates in vitro. Anle138b prevents accumulation of PrPSc in the brain and the spleen. Anle138b exhibits neuroprotective effects in a Parkinson's disease mouse model and improves motor performance in an α-synucleinopathy model.

References: 1. Wagner J. et al. (2013) Acta Neuropathol. 125 (6): 795-813.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-607-25MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-607-25MG
• Package Unit: 25 mg
• Quantity Unit: STK