AR-420626, CAS 1798310-55-0

Formulation: A crystalline solid

Formal Name: ​N-(2,5-dichlorophenyl)-4-(2-furanyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-3-quinolinecarboxamide

Purity: ≥95%

Formula Markup: C21H18Cl2N2O3

Formula Weight: 417,3

Shelf life (days): 1460

CAS Number: 1798310-55-0

Notes: Free fatty acid receptor 3 (FFAR3; GPR41) is a G protein-coupled receptor activated by short chain fatty acids (SCFAs). It is expressed in adipose tissue, the gastrointestinal tract, and the peripheral nervous system, and it is involved in SCFA-dependent energy regulation.{28496} AR-420626 is a selective agonist of FFAR3 (GPR41; IC50 = 117 nM) that does not activate the related receptor FFAR2 (GPR43) at concentrations up to 100 µM.{27420} At 10 µM, it can stimulate a 1.26-fold increased release of glucagon-like peptide-1 from colonic crypt cultures.{28497}

• SKU: CAY17531-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 17531-25
• Package Unit: 25 mg
• Quantity Unit: STK