Formulation: A solid
Formal Name: (1R,3'R,5aR,8aR,9aS)-rel-(-)-tetrahydro-1,1',8,8,11-pentamethyl-spiro[5H,6H-5a,9a-(iminomethano)-1H-cyclopent[f]indolizine-7(8H),3'-pyrrolidine]-2',5',10-trione
Purity: ≥98%
Formula Markup: C20H29N3O3
Formula Weight: 359,5
Shelf life (days): 1460
CAS Number: 195966-93-9
Notes: Aspergillimide is a fungal metabolite originally isolated from A. japonicus.{42741} It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.{42742} Dietary administration of aspergillimide A (10 µg/g of diet) induces paralysis in silkworm fourth instar larvae.{42741} Aspergillimide A (10 and 20 mg/kg) reduces T. colubriformis fecal egg count in gerbils.{46107}
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