Avermectin B1a, CAS 65195-55-3

Avermectin B1a, CAS 65195-55-3
SKU
CAY22000-1
Packaging Unit
1 mg
Manufacturer
Cayman Chemical

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Formulation: A solid

Formal Name: 5-O-demethyl-avermectin A1a

Purity: ≥95%

Formula Markup: C48H72O14

Formula Weight: 873,1

Shelf life (days): 1460

CAS Number: 65195-55-3

Notes: Avermectin B1a is a macrocyclic lactone disaccharide anthelmintic agent that binds to high and low affinity sites on the mammalian GABAA receptor.{35015,35017,35019} Binding to the high affinity site activates the receptor to increase chloride influx, while binding to the low affinity site blocks the channel.{35019} Avermectin B1a inhibits binding of the glycine receptor antagonist strychnine to membranes and the solubilized receptor from rat spinal cord (Kis = 1.3 and 3.6 µM, respectively).{35020} Formulations containing avermectin B1a (>80%) and avermectin B1b (~20%; Item No. 17453) are used in insecticides and veterinary anthelmintic formulas as abamectin (Item No. 19201).{35016,35018}
More Information
SKU CAY22000-1
Manufacturer Cayman Chemical
Manufacturer SKU 22000-1
Green Labware No
Package Unit 1 mg
Quantity Unit STK
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