AZD 4635, CAS 1321514-06-0

Formulation: A crystalline solid

Formal Name: 6-(2-chloro-6-methyl-4-pyridinyl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine

Purity: ≥98%

Formula Markup: C15H11ClFN5

Formula Weight: 315,7

Shelf life (days): 1460

CAS Number: 1321514-06-0

Notes: AZD 4635 is an adenosine A2 receptor antagonist (Ki = 1.7 nM for the human receptor).{47334} It inhibits adenosine-induced cAMP production in CHO cells expressing the human A2 receptor (IC50 = 0.79 μM) and reverses suppression of IFN-γ secretion induced by 5'-N-ethylcarboxamidoadenosine (NECA; Item No. 21420) in CD8+ T cells. AZD 4635 reduces tumor growth when administered alone and in combination with checkpoint inhibitors in syngeneic mouse tumor models.

• SKU: CAY26322-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 26322-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK