AZD 5069, CAS 878385-84-3

Formulation: A crystalline solid

Formal Name: N-[2-[[(2,3-difluorophenyl)methyl]thio]-6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-4-pyrimidinyl]-1-azetidinesulfonamide

Purity: ≥98%

Formula Markup: C18H22F2N4O5S2

Formula Weight: 476,5

Shelf life (days): 1460

CAS Number: 878385-84-3

Notes: AZD 5069 is an antagonist of chemokine receptor 2 (CXCR2; IC50 = 0.79 nM in a radioligand binding assay).{45374} It inhibits CXCL1-induced CD11b expression in and chemotaxis of isolated human neutrophils (pA2s = 6.9 and 9.1, respectively). AZD 5069 (3 and 10 μmol/kg) inhibits bronchoalveolar lavage fluid (BALF) neutrophil influx in a rat model of LPS-induced lung neutrophilia and non-allergic airway inflammation.

• SKU: CAY28297-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28297-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK