AZD 7325, CAS 942437-37-8

Formulation: A solid

Formal Name: 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl-3-cinnolinecarboxamide

Purity: ≥98%

Formula Markup: C19H19FN4O2

Formula Weight: 354,4

Shelf life (days): 1460

CAS Number: 942437-37-8

Notes: AZD 7325 is a positive allosteric modulator of α2- and α3 subunit-containing GABAA receptors and a neutral antagonist for α1 subunit-containing GABAA receptors.{62772} It binds to GABAA receptors in membranes from Sf9 cells expressing α2β3γ2 subunit-containing receptors (Ki = 0.309 nM). AZD 7325 (1 mg/kg) increases marble-burying behavior, indicating anxiety-like activity, and decreases audiogenic seizure severity in the Fmr1-/- mouse model of fragile X syndrome.{62773}

• SKU: CAY36449-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36449-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe