Formulation: A solid
Formal Name: 3-phenyl-1H-naphtho[2,1-b]pyran-1-one
Purity: ≥98%
Formula Markup: C19H12O2
Formula Weight: 272,3
Shelf life (days): 1460
CAS Number: 6051-87-2
Notes: β-Naphthoflavone is a non-carcinogenic agonist of the aryl hydrocarbon receptor (AhR).{54964} It activates transcription of the AhR target gene CYP1A1 when used at concentrations of 1 and 10 µM in HepG2 cells.{54964} β-Naphthoflavone (10 µM) inhibits hydrogen peroxide-induced apoptosis, as well as increases the activity of catalase (CAT) and superoxide dismutase (SOD) and decreases the levels of malondialdehyde (MDA), in SH-SY5Y cells.{54965} It has also been used as a positive control for the induction of AhR transcriptional activity.{54964}