Formulation: A solid
Formal Name: L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valylglycyl-L-arginyl-L-prolyl-L-α-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C130H184N38O31S2 • XCF3COOH
Formula Weight: 2839,2
Shelf life (days): 1460
Notes: BAM-22P is an endogenous neuropeptide derived from proenkephalin A.{64655} It is expressed primarily in the adrenal medulla and at lower concentrations throughout the brain. BAM-22P binds µ-, κ-, and δ-opioid receptors (Kis = 0.9, 2.9, and 7.2 nM, respectively).{64654} Intracerebroventricular administration of BAM-22P induces analgesia in a tail-flick assay in mice (ED50 = 6.4 nM).{64655} It decreases the frequency of tail flicking, as well as paw lifting and licking in a rat model of formalin-induced nocifensive behavior when administered intrathecally at a dose of 5 nM/animal.{64656}
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