BAY-1797, CAS 2055602-83-8

Formulation: A solid

Formal Name: N-[3-(aminosulfonyl)-4-(3-chlorophenoxy)phenyl]-benzeneacetamide

Purity: ≥98%

Formula Markup: C20H17ClN2O4S

Formula Weight: 416,9

Shelf life (days): 1460

CAS Number: 2055602-83-8

Notes: BAY-1797 is an antagonist of the purinergic P2X4 receptor (IC50 = 0.211 µM for the human receptor).{61478} It is selective for P2X4 over P2X1, P2X3, and P2X7 receptors (IC50s = >50, 8.3, and 10.6 µM, respectively, for the human receptors), as well as a panel of G protein-coupled receptors (GPCRs), ion channels, kinases, and transporters at 10 µM. BAY-1797 (50 mg/kg) decreases intraplantar prostaglandin E2 (PGE2; Item No. 14010) levels and reduces non-evoked pain-related behavior in the dynamic weight bearing test in a mouse model of inflammatory pain induced by complete Freund’s adjuvant (CFA).

• SKU: CAY34229-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34229-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK