BAY-899, CAS 2471967-92-5

Formulation: A solid

Formal Name: N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxamide

Purity: ≥98%

Formula Markup: C25H19F2N5O2

Formula Weight: 459,5

Shelf life (days): 1460

CAS Number: 2471967-92-5

Notes: BAY-899 is an antagonist of the luteinizing hormone receptor (LHR; IC50s = 185 and 46 nM for the human and rat receptors, respectively).{51892} It is selective for LHR over thyroid-stimulating hormone (TSH) and follicle-stimulating hormone (FSH) receptors (IC50s = 24 and >16 µM, respectively, for the human receptors) and a panel of 25 G protein-coupled receptors (GPCRs) at 10 µM. BAY-899 (12.5 mg/kg per day) reduces serum levels of estradiol in female rats.

• SKU: CAY41716-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41716-10
• Package Unit: 10 mg
• Quantity Unit: STK