Formulation: A solid
Formal Name: (6S,7S)-6,7-dihydro-6-methyl-7-(phenylmethyl)-quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
Purity: ≥95%
Formula Markup: C24H19N3O2
Formula Weight: 381,4
Shelf life (days): 1460
CAS Number: 157047-96-6
Notes: Benzomalvin A is a fungal metabolite produced by Penicillium.{43022,38039} It inhibits yeast α-glucosidase in vitro (IC50 = 383.2 μM).{43022} In vivo, benzomalvin A (3.1-31.6 mg/kg) decreases plasma glucose levels in mice following administration of sucrose. It also decreases the plasma glucose postprandial peak in nicotinamide-streptozotocin-induced hyperglycemic mice when administered at a dose of 10 mg/kg. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P (Item No. 24035) to guinea pig, rat, and human NK1 (Kis = 12, 42, and 43 μM, respectively).{38039}
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