Shelf life (days): 1460.0
Formulation: A solid
Formal Name: L-leucyl-L-a-glutamyl-L-asparaginyl-L-prolyl-L-seryl-L-prolyl-L-glutaminyl-L-alanyl-L-prolyl-L-alanyl-L-arginyl-L-arginyl-L-leucyl-L-leucyl-L-prolyl-L-proline, acetate
Amino Acids: LENPSPQAPARRLLPP-OH
Purity: ≥90%
Formula Markup: C78H130N24O22 / XC2H4O2
Formula Weight: 1756.01536
Notes: BigLEN is a neuropeptide and fragment of the pro-protein ProSAAS, involved in food intake, and an agonist of the orphan G protein-coupled receptor 171 (GPR171).{67456} It selectively increases intracellular calcium levels in CHO cells expressing GPR171 over those expressing GPR19, GPR108, or GPR165 at 1 µM. BigLEN (10 µM) increases neurite outgrowth in mouse Neuro2a neuroblastoma cells.