BMS 189961, CAS 185629-22-5

Formulation: A crystalline solid

Formal Name: 3-fluoro-4-[[2-hydroxy-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)acetyl]amino]benzoic acid

Purity: ≥98%

Formula Markup: C23H26FNO4

Formula Weight: 399,5

Shelf life (days): 1460

CAS Number: 185629-22-5

Notes: BMS 189961 is an agonist of retinoic acid receptor γ (RARγ; EC50 = 30 nM in a transactivation assay).{52154} It is selective for RARγ over RARβ (EC50 = 1,000 nM). In vitro, BMS 189961 decreases long bone growth and digit formation of isolated mouse embryonic limb buds when used at concentrations of 0.01 and 0.1 µM.{52155} Topical administration of BMS 189661 (40 nmol) increases the skin expression of retinoid metabolism-related genes, including Rdh10, Crabp2, and Krt4, as well as epidermal barrier genes, including Spink5, Klk5, and Klk7, in mice.{52156}

• SKU: CAY29380-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29380-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK