BMS 270394, CAS 262433-54-5

Formulation: A solid

Formal Name: 3-fluoro-4-[[(2R)-2-hydroxy-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)acetyl]amino]-benzoic acid

Purity: ≥98%

Formula Markup: C23H26FNO4

Formula Weight: 399,5

Shelf life (days): 1460

CAS Number: 262433-54-5

Notes: BMS 270394 is an agonist of retinoic acid receptor γ (RARγ; EC50 = 30 nM in a transactivation assay) and the active enantiomer of BMS 189961 (Item No. 29380).{52154} It is selective for RARγ over RARβ (EC50 = 400 nM) and is inactive at RARα. BMS 270394 synergizes with paclitaxel (Item No. 10461) to inhibit the growth of MCF-7 breast and OVCAR-3 ovarian cancer, as well as SqCC/Y1 head and neck squamous cell carcinoma, cells.{61883}

• SKU: CAY35576-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35576-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe