BQ-3020 (trifluoroacetate salt)

Formulation: A solid

Formal Name: N-acetyl-11-L-alanine-15-L-alanine-6-21-endothelin 1 (swine reduced), trifluoroacetate salt

Purity: ≥90%

Formula Markup: C96H140N20O25S • XCF3COOH

Formula Weight: 2006,3

Shelf life (days): 1460

Notes: BQ-3020 is a peptide endothelin type B (ETB) receptor agonist.{58930} It selectively binds to ETB over ETA receptors (IC50s = 0.07 and 940 nM, respectively) and induces inositol triphosphate formation and calcium mobilization in isolated bovine carotid artery endothelial cells.{58930,58932} BQ-3020 increases or decreases renal perfusion pressure in Dahl salt-resistant or -sensitive rats, respectively.{58933} It decreases the production of nitric oxide (NO) and induces vasoconstriction in a rat model of diet-induced hypercholesterolemia.

• SKU: CAY34014-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34014-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe