C-176, CAS 314054-00-7

Formulation: A crystalline solid

Formal Name: N-(4-iodophenyl)-5-nitro-2-furancarboxamide

Purity: ≥98%

Formula Markup: C11H7IN2O4

Formula Weight: 358,1

Shelf life (days): 1460

CAS Number: 314054-00-7

Notes: C-176 is a covalent inhibitor of stimulator of interferon genes (STING).{35390} It selectively reduces STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.01 to 5 μM. C-176 reduces serum levels of type-I interferons (IFNs) and cardiac inflammation in the Trex-/- mouse model of multi-organ inflammation.

• SKU: CAY25859-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 25859-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK