Formulation: A solid
Formal Name: N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-5'-adenylic acid, anhydride with P,P'-(dichloromethylene)bis[phosphonic acid], tetrasodium salt
Purity: ≥98%
Formula Markup: C17H21Cl2F3N5O12P3S2 • 4Na
Formula Weight: 864,3
Shelf life (days): 1460
CAS Number: 163706-36-3
Notes: Cangrelor is an ATP analog that inhibits platelet aggregation (IC50 = 0.4 nM).{40206} It is a reversible competitive antagonist of the platelet purinergic P2Y12 receptor.{23699,40207} Pretreatment with cangrelor significantly reduces blood clotting induced by ADP in a mouse model of pulmonary thromboembolism.{40208} Formulations containing cangrelor have been used to prevent blood clotting in at-risk patients.{40209}