Carvacrol, CAS 499-75-2

Formulation: A liquid

Formal Name: 2-methyl-5-(1-methylethyl)-phenol

Purity: ≥98%

Formula Markup: C10H14O

Formula Weight: 150,2

Shelf life (days): 730

CAS Number: 499-75-2

Notes: Carvacrol is a monoterpene that has been found in O. vulgare, and has diverse biological activities.{58477} It induces currents in HEK293 cells expressing mouse transient receptor potential vanilloid 3 (TRPV3) or rat TRP ankyrin A1 (TRPA1) when used at concentrations of 500 and 250 µM, respectively.{58478} It also inhibits constitutive activation of TRP melastatin 7 (TRPM7) expressed in HEK293 cells (IC50 = 306 µM).{58479} Carvacrol is active against various strains of P. aeruginosa (MICs = 0.3-0.13 µg/ml) and a variety of plant pathogenic fungi, including A. niger, A. ochraceus, Cladosporium, and F. oxysporum (MICs = 50, 100, 100, and 125 µg/ml, respectively).{58480,58578}. It decreases rat brain, liver, and kidney levels of malondialdehyde (MDA), as well as increases superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase (GR), and catalase activities in the same tissues when administered at a dose of 40 mg/kg.{58481} Carvacrol (15 mg/kg) decreases the number of liver tumor nodules in a rat model of diethylnitrosamine-induced hepatocarcinogenesis.{58482} Formulations containing carvacrol have been used as flavoring agents.

• SKU: CAY33753-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33753-100
• Green Labware: No
• Package Unit: 100 g
• Quantity Unit: STK